According to the latest report published by Credence Research, Inc. “Organ on Chip Market – Growth, Future Prospects and Competitive Analysis, 2018-2026,” the global organ on chip market is expected to witness significant growth.
Direct recognition and investigation of biomolecules and cells in physiological microenvironment is essential for quick assessment of pharmacy and biology. The past several years have seen surprising improvements in the development of in vitro organs and tissues model with various purposes based on microfluidic devices known as organ on chip.
Organ on chip technology aims at creating imitation active organs that mimic the complex and biological reactions of actual organs, keeping in mind the goal to examine drugs’ action by exactly manipulating the cells and their microenvironments. To accomplish this, the artificial organs ought to be micro fabricated with an extracellular matrix (ECM) and different sorts of cells, and recapitulate morphogenesis, cell differentiation, and functions corresponding the local organ.
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Based on the product types, the global organ on chip market is segmented into lungs on chip, heart on chip, liver on chip, kidney on chip, and others; additionally the end users studied in this report are categorized into research institutes, and pharmaceutical manufacturers. Advancement in technology of organ on chip is capable of accelerating the speed of drug testing, producing more reliable data, and dropping the financial and ethical drawbacks of preclinical research will boost the market of organ on chip.
Geographically, the overall organ on chip market is projected for Middle East and Africa, Europe, Latin America, Asia Pacific, and North America. As for revenue share, North America leads the global market and is expected that the situation will remain consistent amid the forecast period. Though the control of North America on the global market will be clearly challenged by Asia Pacific. The need of organ on chip has become prominent in Asia Pacific because of growth in the healthcare infrastructure, healthcare expenditure, and flexible income. There are massive chances for market diffusion in nations like India, Mexico, and China to the market occupants already having a grip in developed countries.
- Other Organs
- Physiological Model Development
- Drug Discovery
- Toxicology Research
An organ-on-a-chip (OOC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems, a type of artificial organ.It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.
Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.
Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. “If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles” says William Haseltine, founder of Human Genome Sciences in Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions. Source- Wikipedia